V92™ Cellular Bone Matrix

V92™ Cellular Bone Matrix

The V92™ product line: V92™ and V92™-FC are viable allogeneic bone allografts intended for use in bone remodeling. The V92™ products are safe and non-immunogenic and provide an ideal alternative to autograft in a variety of orthopaedic and spine applications.

The V92™  cellular bone matrices are viable allogeneic bone allografts containing viable bone-derived cells. Each V92™ product contains the three key elements that are ideal for bone formation:

  • An osteoconductive three-dimensional scaffold with cortical and cancellous components.
  • A demineralized bone scaffold with osteoinductive potential which provides exposure of signaling molecules and bone morphogenetic proteins.1
  • Bone-derived cells to support osteogenic healing processes.

The V92™  product line is prepared with a novel DMSO-free cryoprotectant, which provides dependable cell identity and the ability to sustain cell viability post-thaw. Final preparation of the cell and bone components yields a product that provides osteoconductive, osteoinductive, and osteogenic properties to enhance the patients’s innate healing response

Key Features

  • Two unique scaffold blends for optimal handling characteristics: V92™ and V92™-FC
  • Proprietary, optimized bone microparticulate size range of 100-300 μm.2
  • Novel DMSO-free cryoprotectant, with no rinsing and decanting steps required prior to use.
  • Average cell viability of the cell component exceeds 80% post-thaw.3
  • Minimum of 150,000 viable cells per cc of allograft post-thaw.3
  • Convenient handling and preparation in the OR, with total preparation time on the back table less than 20 minutes.
  • Four (4) hour working window for implantation after thaw without loss of cell viability.
  • Product shelf-life is two (2) years from date of processing when stored at -65°C or colder.
  1. Gruskin, E. et.al., Demineralized bone matrix in bone repair: history and use. Advanced Drug Delivery Reviews, 2012. 64:1063-1077.
  2. Malinin, T.I., et. al., Particulate bone allograft incorporation in regeneration of osseous defects; importance of particle sizes. The Open Orthopeadics Journal, 2007. 1:19-24.
  3. Data on file at Vivex Biomedical, Inc.

If you are a surgeon and would like more information or to book a case using the PRESERVE™ V92™ Cellular Bone Matrix, please enter your name and office phone number below.



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