PRO3™ Flowable

Pro3™ Amniotic Fluid

Pro3™-F (frozen) and Pro3™-FA (ambient). Pro3™-F and Pro3′”-FA are all-natural liquid matrix allografts derived from amniotic fluid. Naturally present to protect the fetus, amniotic fluid provides the ideal environment to support fetal growth.1 The cushioning effect of amniotic fluid in utero shields the fetus from outside pressures, acting as a shock absorber.2

Much the same as the in utero environment, Pro3™ Flowable principally functions to cushion surface articulation within the joint capsule.The most essential functions of the joint capsule are to provide shock absorption, lubrication, and joint stability. When injury or degradationcauses cushioning to decline, discomfort can result as the body’s natural shock absorbers wear out.3

Safety and Versatility

  • Amniotic fluid is recovered from healthy mothers who have undergone Cesarean section delivery
  • Pro3™ Flowable is processed using minimally manipulative procedures that have been shown to successfully preserve the natural composition of amniotic fluid
  • E-Beam terminal sterilization provides sterility assurance level (SAL) of 1 Q-6 

Pro3™-Flowable is available in two configurations offering increased versatility:

  • Configurations:

– Frozen Temperature, -40°C or Colder (Pro3′”-F)

– Ambient Temperature, 2°C to 30°C (Pro3T”-FA)

  • 2-year shelf-life at frozen temperature (Pro3T”-F)
  • 2-year shelf-life at ambient temperature (Pro3T”-FA)
  • Easily applied with a 30g or larger needle directly to the site of augmentation, injury, or pain


1. Seeds AE: Amniotic fluid physiology in Sciarra JJ {ed): Gynecology and Obstetrics, Vol 3. New York, Harper & Row, 1989.

2. Shohnazi M, et al., The Effects of Intravenous Hydration on Amniotic Fluid Volume and Pregnancy Outcomes in Women with Term Pregnancy and Oligohydromnios: A Randomized Clinical Trial. Journal of Caring Sciences. September 2012; 1 {3):123-128.

3. Hui, A.Y., et al., A Systems Biology Approach to Synovial Joint Lubrication in Health, Injury, and Disease. Wiley lnterdisc Rev Sys! Biol Med. 2012; 4{1) : 15-37.

If you are a surgeon and would like more information or to book a case using the

Pro3™ Flowable, please enter your name and office phone number below.



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